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TW-Algal产品参数描述

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    Microcystin-LR 微囊藻毒素LR

     

    Description

    Cyclic heptapeptide isolated from the freshwater cyanobacteria
    Microcystis aeruginosa. Potent inhibitor of protein phosphatase type 1 (PP1) and protein
    phosphatase type 2A (PP2A); has no effect on protein kinase.

     

    Molecular formula   C49H74N10O12

     

    Molecular weigh  995.2

     

    Case Number  101043-37-2

     

    Solubility  MeOH, EtOH or DMSO

     

    Storage  Stable in -25 ℃ for 2 year

     

    Form  Lyophilized solid

     

    Appearance(color)  White to off-White

     

    Purity  ≥ 95% by HPLC

     

    Method


    Material:
      Microcystin-LR (MCYST-LR), 1.25 μg/μl
    Column:  Biosil 5 ODS-U, 4.6mm i.d. x 250mm
    Mobile phase:  0.01M ammonium acetate/CH3CN = 75/25
    Flow rate:  1 ml/min
    Detection:  ABS at 238 nm on the Hitachi 7400 UV-VIS detector

    ______________________________________________________________________________________________________

    Microcystin-RR 微囊藻毒素RR

     

    Description

    Analog of MCYST-LR (Cat. No. AD0100) Arg group substituted in
    place of Leu. Inhibitor of protein phosphatase type 2A with lower toxicity than
    microcystin LR.

     

    Molecular formula C49H75N13O12

     

    Molecular weigh 1038.2

     

    Case Number 111755-37-4

     

    Solubility Water, MeOH or DMSO

     

    Storage Stable in -25 ℃ for 2 year

     

     

    Form  Lyophilized solid

     

    Appearance(color)  White to off-White

     

    Purity  ≥ 95% by HPLC

     

    Method

     

    Material:  Microcystin-RR (MCYST-RR), 20 μg
    Column:  Thermo Quest Hyperprep HS ODS 8μ, 10x250 mm
    Mobile phase:  0.01M ammonium acetate/MeOH = 42/58
    Flow rate:  3 ml/min
    Detection:  ABS at 238 nm

    ______________________________________________________________________________________________________

    Okadaic acid 大田软海绵酸、冈田酸、黑海绵酸

     

    Description

    An ionophore-like polyether isolated from marine dinoflagellate
    Prorocentrum lima. Implicated as causative agent of diarrhetic shellfish
    poisoning. Potent inhibitor of protein phosphatase type 1 (PP1) and
    protein phosphatase type 2A (PP2A). Useful for the study of protein
    phosphatases in cell extracts as well as intact cells.

     

    Molecular formula  C44H68O13

     

    Molecular weigh  804.5

     

    Case Number  78111-17-8

     

    Solubility  MeOH, EtOH or DMSO

     

    Storage  Stable in -25 ℃ for 2 year

     

     

    Form  White crystal solid

     

    Appearance(color)  White to off-White

     

    Purity  ≥ 95% by HPLC

     

    Method

     

    Material:  Okadaic acid (OA) 20 μg, 1 mg/ml ACN
    Column:  Angilent HC-C18 5μ 4.6x250mm
    Mobile phase:  0.1% acetic acid in H2O/CH3CN = 40/60
    Flow rate:  1 ml/min
    Detection:  ABS at 205 nm on the Hitachi 7400 UV-VIS detector

    ______________________________________________________________________________________________________

     

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